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Test Name REF LAB LUNG CANCER (NSCLC) ROS1 (6Q22) REARRANGEFISH
Orderable CPT -
OVT 123002560
Synonyms -
Result Test Name QUEST SPECIMEN TYPE/SOURCE
Laboratory QUEST LAB
Result Test Code 12386025621
Laboratory Test Name QUEST LUNG CANCER (NSCLC) ROS1 (6Q22) REARRANGEFISH
Reportable Test Name -
Result LOINC 51968-6
Collection Container PATH CONTAINER
Units -
Collection Requirements Preferred Specimen(s) Formalin-fixed paraffin-embedded tissue block Alternative Specimen(s) 5x5 mm tumor tissue in culture transport medium 4-5 microns sections on charged slide (x5) Collection Instructions Lung tissue biopsy formalin fixed paraffin-embedded block or charged/+slides from formalin fixed paraffin embedded tissue. Specimen MUST be fixed with 10% neutral buffered formalin. Fixation between 6 and 48 hours is recommended. Pathology report must accompany paraffin block or slides. Information required in this report includes: Physician identification specimen identifiers (case and block number) specimen site and type tissue processing used (routine or microwave) type of fixative time and duration of fixation pathologic diagnosis.
Container Temp Room Temperature (1)
Container Volume -
Test Info Lung Cancer (NSCLC) ROS1 (6q22) Rearrangement FISH - ROS1 rearrangement has been identified in 1.7% of non small-cell lung cancer (NSCLC) by using a FISH assay. Treatment with ALK/MET tyrosine kinase inhibitors such as crizotinib (Xalkori(R)) has shown early evidence of therapeutic efficacy in ROS1-rearranged NSCLC (Bergethon et al. J Clin Oncol. 2012;30:863-870)
Shipping Instructions Transport Container Formalin-fixed paraffin-embedded tissue block Transport Temperature Room temperature Specimen Stability Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.
Result Test Name QUEST PRIOR THERAPY/TRANSPLANT
Laboratory QUEST LAB
Result Test Code 12386001207
Laboratory Test Name QUEST LUNG CANCER (NSCLC) ROS1 (6Q22) REARRANGEFISH
Reportable Test Name -
Result LOINC 43368-0
Collection Container PATH CONTAINER
Units -
Collection Requirements Preferred Specimen(s) Formalin-fixed paraffin-embedded tissue block Alternative Specimen(s) 5x5 mm tumor tissue in culture transport medium 4-5 microns sections on charged slide (x5) Collection Instructions Lung tissue biopsy formalin fixed paraffin-embedded block or charged/+slides from formalin fixed paraffin embedded tissue. Specimen MUST be fixed with 10% neutral buffered formalin. Fixation between 6 and 48 hours is recommended. Pathology report must accompany paraffin block or slides. Information required in this report includes: Physician identification specimen identifiers (case and block number) specimen site and type tissue processing used (routine or microwave) type of fixative time and duration of fixation pathologic diagnosis.
Container Temp Room Temperature (1)
Container Volume -
Test Info Lung Cancer (NSCLC) ROS1 (6q22) Rearrangement FISH - ROS1 rearrangement has been identified in 1.7% of non small-cell lung cancer (NSCLC) by using a FISH assay. Treatment with ALK/MET tyrosine kinase inhibitors such as crizotinib (Xalkori(R)) has shown early evidence of therapeutic efficacy in ROS1-rearranged NSCLC (Bergethon et al. J Clin Oncol. 2012;30:863-870)
Shipping Instructions Transport Container Formalin-fixed paraffin-embedded tissue block Transport Temperature Room temperature Specimen Stability Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.
Result Test Name QUEST LUNG CANCER (NSCLC) ROS1 (6Q22) REARRANGEFISH
Laboratory QUEST LAB
Result Test Code 12386010035
Laboratory Test Name QUEST LUNG CANCER (NSCLC) ROS1 (6Q22) REARRANGEFISH
Reportable Test Name -
Result LOINC 30896-5
Collection Container PATH CONTAINER
Units -
Collection Requirements Preferred Specimen(s) Formalin-fixed paraffin-embedded tissue block Alternative Specimen(s) 5x5 mm tumor tissue in culture transport medium 4-5 microns sections on charged slide (x5) Collection Instructions Lung tissue biopsy formalin fixed paraffin-embedded block or charged/+slides from formalin fixed paraffin embedded tissue. Specimen MUST be fixed with 10% neutral buffered formalin. Fixation between 6 and 48 hours is recommended. Pathology report must accompany paraffin block or slides. Information required in this report includes: Physician identification specimen identifiers (case and block number) specimen site and type tissue processing used (routine or microwave) type of fixative time and duration of fixation pathologic diagnosis.
Container Temp Room Temperature (1)
Container Volume -
Test Info Lung Cancer (NSCLC) ROS1 (6q22) Rearrangement FISH - ROS1 rearrangement has been identified in 1.7% of non small-cell lung cancer (NSCLC) by using a FISH assay. Treatment with ALK/MET tyrosine kinase inhibitors such as crizotinib (Xalkori(R)) has shown early evidence of therapeutic efficacy in ROS1-rearranged NSCLC (Bergethon et al. J Clin Oncol. 2012;30:863-870)
Shipping Instructions Transport Container Formalin-fixed paraffin-embedded tissue block Transport Temperature Room temperature Specimen Stability Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.
Result Test Name CLINICAL INDICATION:
Laboratory QUEST LAB
Result Test Code 123012211
Laboratory Test Name QUEST LUNG CANCER (NSCLC) ROS1 (6Q22) REARRANGEFISH
Reportable Test Name -
Result LOINC 55752-0
Collection Container PATH CONTAINER
Units -
Collection Requirements Preferred Specimen(s) Formalin-fixed paraffin-embedded tissue block Alternative Specimen(s) 5x5 mm tumor tissue in culture transport medium 4-5 microns sections on charged slide (x5) Collection Instructions Lung tissue biopsy formalin fixed paraffin-embedded block or charged/+slides from formalin fixed paraffin embedded tissue. Specimen MUST be fixed with 10% neutral buffered formalin. Fixation between 6 and 48 hours is recommended. Pathology report must accompany paraffin block or slides. Information required in this report includes: Physician identification specimen identifiers (case and block number) specimen site and type tissue processing used (routine or microwave) type of fixative time and duration of fixation pathologic diagnosis.
Container Temp Room Temperature (1)
Container Volume -
Test Info Lung Cancer (NSCLC) ROS1 (6q22) Rearrangement FISH - ROS1 rearrangement has been identified in 1.7% of non small-cell lung cancer (NSCLC) by using a FISH assay. Treatment with ALK/MET tyrosine kinase inhibitors such as crizotinib (Xalkori(R)) has shown early evidence of therapeutic efficacy in ROS1-rearranged NSCLC (Bergethon et al. J Clin Oncol. 2012;30:863-870)
Shipping Instructions Transport Container Formalin-fixed paraffin-embedded tissue block Transport Temperature Room temperature Specimen Stability Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.