Result Test Name
QUEST VARIANT FREQUENCY 6
Laboratory
QUEST LAB
Result Test Code
12386010218
Laboratory Test Name
QUEST SOLID TUMOR CORE PANEL
Reportable Test Name
-
Result LOINC
-
Collection Container
PATH CONTAINER
Units
-
Collection Requirements
Preferred Specimen(s) 200 mm2 >=20% tumor content of tumor tissue collected in a formalin-fixed paraffin-embedded tissue Alternative Specimen(s) 10 X 10 um (minimum 5 x 10 um) unstained sections of formalin-fixed paraffin-embedded tissue and 1 x 4 um (minimum 1 x 5 um) section with H & E staining >=20% tumor content (minimum >=10% tumor content) Formalin-fixed paraffin-embedded FNA 50 uL of 20 ng/uL (minimum 10 uL of 10 ng/uL) extracted DNA Minimum Volume 10 mm2 >=10% tumor content Collection Instructions For FFPE and slides a pathology report must be submitted with sample. Do not reject.
Container Temp
Room Temperature (1)
Container Volume
-
Test Info
Solid Tumor Core Panel - Solid Tumor Genomics from Quest Advanced Diagnostics - Precision medicine is an emerging approach for disease prevention and treatment that takes individual variability into account. This next-generation sequencing (NGS) panel along with the computational resources and tools that process and analyze the data allows the characterization of individual patients and tumor types. Guidelines exist for using results from many of these genes for selection of FDA approved therapies. This NGS panel can accurately and sensitively sequence more target genes with less DNA with reduced cost time and labor as compared with more limited sequencing methods and the physician can become aware of alternative treatments available to the patient based on presence of mutations in other genes the physicians might not have considered. Microsatellite instability (MSI) and tumor mutation burden (TMB) are also included. The panel allows the generation of diverse data obtained and anal*
Shipping Instructions
Transport Temperature Room temperature Specimen Stability Tumor tissue Room temperature: 5 years Refrigerated: 5 years Frozen: Unacceptable Unstained sections of FFPE tissue and H & E stained section Room temperature: 28 days Refrigerated: 5 years Frozen: Unacceptable FFPE FNA Room temperature: 5 years Refrigerated: 5 years Frozen: Unacceptable Extracted DNA Room temperature: 14 days Refrigerated: 90 days Frozen: 5 years Reject Criteria Sample with <10% tumor content Sample less than minimal requirements