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Test Name REF LAB ANA SCREENIFA WITH REFLEX TO TITER AND PATTERN/SJOGREN'S PANE1
Orderable CPT -
OVT 12300096151
Synonyms 90077
Result Test Name SJOGREN'S ANTIBODY SS-B
Laboratory QUEST LAB
Result Test Code 123012721
Laboratory Test Name QUEST ANA SCREENIFA WITH REFLEX TO TITER AND PATTERN/SJOGREN'S PANEL 1
Reportable Test Name -
Result LOINC 45142-7
Collection Container SST
Units -
Collection Requirements Preferred Specimen(s) 2 mL serum Minimum Volume 1.5 mL
Container Temp Room Temperature (1)
Container Volume 1.500
Test Info ANA ScreenIFA with Reflex to Titer and Pattern/Sjogren's Panel 1 - This panel can be helpful in the diagnosis of Sjogren syndrome by simultaneously testing for antinuclear antibodies (ANAs) with an immunofluorescence assay (IFA) performed on human epithelial type 2 (HEp-2) cells as well as SSA antibodies SSB antibodies and rheumatoid factor (RF). For specimens with positive ANA IFA results reflex testing for ANA titer and pattern is performed. The laboratory evaluation for individuals with clinical suspicion of autoimmune diseases often begins with an ANA screen. The classic ANA IFA on HEp-2 cells is considered by the American College of Rheumatology (ACR) as the current gold standard because of its overall high sensitivity for several autoimmune diseases [1]. Knowing the ANA titer and pattern can be helpful in interpreting positive ANA results [2]. Individuals with negative results on the ANA IFA usually also have negative results on specific autoantibodies. However SSA antibody may be detected in some ANA IFA-negative patients with lupus or Sjogren syndrome [3]. The 2012 ACR classification criteria for Sjogren syndrome indicate that testing for SSA or SSB antibody has the highest sensitivity and specificity and that a positive RF result in addition to an ANA titer >=1:320 is consistent with Sjogren syndrome [4]. However the 2016 ACR/European League Against Rheumatism (EULAR) classification criteria for Sjogren syndrome do not include SSB/La RF and ANA titer because studies showed that these markers do not add sufficient value to SSA/Ro testing [5]. The results of this test should be interpreted in the context of pertinent clinical and family history and physical examination findings.
Shipping Instructions Transport Container Transport tube Transport Temperature Room temperature Specimen Stability Room temperature: 4 days Refrigerated: 7 days Frozen: 30 days Reject Criteria Gross hemolysis Grossly lipemic Grossly icteric Microbial contamination may interfere
Result Test Name ANTINUCLEAR ANTIBODY SCREEN IFA
Laboratory QUEST LAB
Result Test Code 123012718
Laboratory Test Name QUEST ANA SCREENIFA WITH REFLEX TO TITER AND PATTERN/SJOGREN'S PANEL 1
Reportable Test Name -
Result LOINC 42254-3
Collection Container SST
Units -
Collection Requirements Preferred Specimen(s) 2 mL serum Minimum Volume 1.5 mL
Container Temp Room Temperature (1)
Container Volume 1.500
Test Info ANA ScreenIFA with Reflex to Titer and Pattern/Sjogren's Panel 1 - This panel can be helpful in the diagnosis of Sjogren syndrome by simultaneously testing for antinuclear antibodies (ANAs) with an immunofluorescence assay (IFA) performed on human epithelial type 2 (HEp-2) cells as well as SSA antibodies SSB antibodies and rheumatoid factor (RF). For specimens with positive ANA IFA results reflex testing for ANA titer and pattern is performed. The laboratory evaluation for individuals with clinical suspicion of autoimmune diseases often begins with an ANA screen. The classic ANA IFA on HEp-2 cells is considered by the American College of Rheumatology (ACR) as the current gold standard because of its overall high sensitivity for several autoimmune diseases [1]. Knowing the ANA titer and pattern can be helpful in interpreting positive ANA results [2]. Individuals with negative results on the ANA IFA usually also have negative results on specific autoantibodies. However SSA antibody may be detected in some ANA IFA-negative patients with lupus or Sjogren syndrome [3]. The 2012 ACR classification criteria for Sjogren syndrome indicate that testing for SSA or SSB antibody has the highest sensitivity and specificity and that a positive RF result in addition to an ANA titer >=1:320 is consistent with Sjogren syndrome [4]. However the 2016 ACR/European League Against Rheumatism (EULAR) classification criteria for Sjogren syndrome do not include SSB/La RF and ANA titer because studies showed that these markers do not add sufficient value to SSA/Ro testing [5]. The results of this test should be interpreted in the context of pertinent clinical and family history and physical examination findings.
Shipping Instructions Transport Container Transport tube Transport Temperature Room temperature Specimen Stability Room temperature: 4 days Refrigerated: 7 days Frozen: 30 days Reject Criteria Gross hemolysis Grossly lipemic Grossly icteric Microbial contamination may interfere
Result Test Name QUEST INTERPRETATION
Laboratory QUEST LAB
Result Test Code 12345004380
Laboratory Test Name QUEST ANA SCREENIFA WITH REFLEX TO TITER AND PATTERN/SJOGREN'S PANEL 1
Reportable Test Name -
Result LOINC -
Collection Container SST
Units -
Collection Requirements Preferred Specimen(s) 2 mL serum Minimum Volume 1.5 mL
Container Temp Room Temperature (1)
Container Volume 1.500
Test Info ANA ScreenIFA with Reflex to Titer and Pattern/Sjogren's Panel 1 - This panel can be helpful in the diagnosis of Sjogren syndrome by simultaneously testing for antinuclear antibodies (ANAs) with an immunofluorescence assay (IFA) performed on human epithelial type 2 (HEp-2) cells as well as SSA antibodies SSB antibodies and rheumatoid factor (RF). For specimens with positive ANA IFA results reflex testing for ANA titer and pattern is performed. The laboratory evaluation for individuals with clinical suspicion of autoimmune diseases often begins with an ANA screen. The classic ANA IFA on HEp-2 cells is considered by the American College of Rheumatology (ACR) as the current gold standard because of its overall high sensitivity for several autoimmune diseases [1]. Knowing the ANA titer and pattern can be helpful in interpreting positive ANA results [2]. Individuals with negative results on the ANA IFA usually also have negative results on specific autoantibodies. However SSA antibody may be detected in some ANA IFA-negative patients with lupus or Sjogren syndrome [3]. The 2012 ACR classification criteria for Sjogren syndrome indicate that testing for SSA or SSB antibody has the highest sensitivity and specificity and that a positive RF result in addition to an ANA titer >=1:320 is consistent with Sjogren syndrome [4]. However the 2016 ACR/European League Against Rheumatism (EULAR) classification criteria for Sjogren syndrome do not include SSB/La RF and ANA titer because studies showed that these markers do not add sufficient value to SSA/Ro testing [5]. The results of this test should be interpreted in the context of pertinent clinical and family history and physical examination findings.
Shipping Instructions Transport Container Transport tube Transport Temperature Room temperature Specimen Stability Room temperature: 4 days Refrigerated: 7 days Frozen: 30 days Reject Criteria Gross hemolysis Grossly lipemic Grossly icteric Microbial contamination may interfere
Result Test Name SJOGREN'S ANTIBODY SS-A
Laboratory QUEST LAB
Result Test Code 123012720
Laboratory Test Name QUEST ANA SCREENIFA WITH REFLEX TO TITER AND PATTERN/SJOGREN'S PANEL 1
Reportable Test Name -
Result LOINC 33569-5
Collection Container SST
Units -
Collection Requirements Preferred Specimen(s) 2 mL serum Minimum Volume 1.5 mL
Container Temp Room Temperature (1)
Container Volume 1.500
Test Info ANA ScreenIFA with Reflex to Titer and Pattern/Sjogren's Panel 1 - This panel can be helpful in the diagnosis of Sjogren syndrome by simultaneously testing for antinuclear antibodies (ANAs) with an immunofluorescence assay (IFA) performed on human epithelial type 2 (HEp-2) cells as well as SSA antibodies SSB antibodies and rheumatoid factor (RF). For specimens with positive ANA IFA results reflex testing for ANA titer and pattern is performed. The laboratory evaluation for individuals with clinical suspicion of autoimmune diseases often begins with an ANA screen. The classic ANA IFA on HEp-2 cells is considered by the American College of Rheumatology (ACR) as the current gold standard because of its overall high sensitivity for several autoimmune diseases [1]. Knowing the ANA titer and pattern can be helpful in interpreting positive ANA results [2]. Individuals with negative results on the ANA IFA usually also have negative results on specific autoantibodies. However SSA antibody may be detected in some ANA IFA-negative patients with lupus or Sjogren syndrome [3]. The 2012 ACR classification criteria for Sjogren syndrome indicate that testing for SSA or SSB antibody has the highest sensitivity and specificity and that a positive RF result in addition to an ANA titer >=1:320 is consistent with Sjogren syndrome [4]. However the 2016 ACR/European League Against Rheumatism (EULAR) classification criteria for Sjogren syndrome do not include SSB/La RF and ANA titer because studies showed that these markers do not add sufficient value to SSA/Ro testing [5]. The results of this test should be interpreted in the context of pertinent clinical and family history and physical examination findings.
Shipping Instructions Transport Container Transport tube Transport Temperature Room temperature Specimen Stability Room temperature: 4 days Refrigerated: 7 days Frozen: 30 days Reject Criteria Gross hemolysis Grossly lipemic Grossly icteric Microbial contamination may interfere
Result Test Name RHEUMATOID FACTOR
Laboratory QUEST LAB
Result Test Code 123012719
Laboratory Test Name QUEST ANA SCREENIFA WITH REFLEX TO TITER AND PATTERN/SJOGREN'S PANEL 1
Reportable Test Name -
Result LOINC 11572-5
Collection Container SST
Units -
Collection Requirements Preferred Specimen(s) 2 mL serum Minimum Volume 1.5 mL
Container Temp Room Temperature (1)
Container Volume 1.500
Test Info ANA ScreenIFA with Reflex to Titer and Pattern/Sjogren's Panel 1 - This panel can be helpful in the diagnosis of Sjogren syndrome by simultaneously testing for antinuclear antibodies (ANAs) with an immunofluorescence assay (IFA) performed on human epithelial type 2 (HEp-2) cells as well as SSA antibodies SSB antibodies and rheumatoid factor (RF). For specimens with positive ANA IFA results reflex testing for ANA titer and pattern is performed. The laboratory evaluation for individuals with clinical suspicion of autoimmune diseases often begins with an ANA screen. The classic ANA IFA on HEp-2 cells is considered by the American College of Rheumatology (ACR) as the current gold standard because of its overall high sensitivity for several autoimmune diseases [1]. Knowing the ANA titer and pattern can be helpful in interpreting positive ANA results [2]. Individuals with negative results on the ANA IFA usually also have negative results on specific autoantibodies. However SSA antibody may be detected in some ANA IFA-negative patients with lupus or Sjogren syndrome [3]. The 2012 ACR classification criteria for Sjogren syndrome indicate that testing for SSA or SSB antibody has the highest sensitivity and specificity and that a positive RF result in addition to an ANA titer >=1:320 is consistent with Sjogren syndrome [4]. However the 2016 ACR/European League Against Rheumatism (EULAR) classification criteria for Sjogren syndrome do not include SSB/La RF and ANA titer because studies showed that these markers do not add sufficient value to SSA/Ro testing [5]. The results of this test should be interpreted in the context of pertinent clinical and family history and physical examination findings.
Shipping Instructions Transport Container Transport tube Transport Temperature Room temperature Specimen Stability Room temperature: 4 days Refrigerated: 7 days Frozen: 30 days Reject Criteria Gross hemolysis Grossly lipemic Grossly icteric Microbial contamination may interfere